Aldehydesilane Coating (AL)

Aldehydesilane Coating (AL)

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Aldehydesilane Coating (AL)

The NEXTERION® AL coating represents a uniform surface featuring aldehyde groups, that are readily reactive to primary amines in order to bind all types of amino-containing or amino-modified bio-molecules.

The covalent bond formed at the terminus of the nucleic acid offers both: stability and maximal base pairing opportunity. The covalent binding diminishes sample loss during the course of experiments and permits stringent washing steps, which reduce background noise and allow greater sensitivity. Additional immobilization steps, such as baking or UV cross-linking, are not required for immobilization.

Produced in ISO class 5 clean room conditions using a standardized process and running a stringent quality control system, aldehydesilane coated substrates are available in standard and custom formats.

Product Information
  • Coating Chemistry
  • Shelf Life
    Nine months for sealed packages at room temperature.
  • Immobilization Method
    Covalent binding via amine reactive chemistry.

  • Probe Types
    • Amino-modified PCR products and BACs/YACs
    • Amino-modified oligonucleotides
    • Small protein fragments such as peptides

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